Compile Data Set for Download or QSAR
maximum 50k data
Found 8 of ki data for polymerid = 3033
TargetProkineticin receptor 2(Homo sapiens (Human))
The Regents of The University of California

US Patent
LigandPNGBDBM463312((-)-(2R)-1-(benzimidazol-4- ylmethyl)-N-(9-chloro-...)
Affinity DataKi:  1.30nMAssay Description:An aequorin-based luminescent assay for calcium mobilization was used to measure mobilization of intracellular Ca2+ (Bullock et al., Mol Pharmacol 65...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProkineticin receptor 2(Homo sapiens (Human))
The Regents of The University of California

US Patent
LigandPNGBDBM463307((-)-(3R)-1-(benzimidazol-4- ylmethyl)-N-(9-chloro-...)
Affinity DataKi:  1.70nMAssay Description:An aequorin-based luminescent assay for calcium mobilization was used to measure mobilization of intracellular Ca2+ (Bullock et al., Mol Pharmacol 65...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProkineticin receptor 2(Homo sapiens (Human))
The Regents of The University of California

US Patent
LigandPNGBDBM463306((-)-(2R)-1-(4-Fluoro-3- methoxybenzyl)-N-(9-chloro...)
Affinity DataKi:  1.90nMAssay Description:An aequorin-based luminescent assay for calcium mobilization was used to measure mobilization of intracellular Ca2+ (Bullock et al., Mol Pharmacol 65...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProkineticin receptor 2(Homo sapiens (Human))
The Regents of The University of California

US Patent
LigandPNGBDBM463309((+-)-2-Methyl-3-(benzimidazol- 4-ylmethylamino)-N-...)
Affinity DataKi:  2.10nMAssay Description:An aequorin-based luminescent assay for calcium mobilization was used to measure mobilization of intracellular Ca2+ (Bullock et al., Mol Pharmacol 65...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProkineticin receptor 2(Homo sapiens (Human))
The Regents of The University of California

US Patent
LigandPNGBDBM463311((-)-(3R)-1-(benzimidazol-4- ylmethyl)-N-(9-chloro-...)
Affinity DataKi:  3nMAssay Description:An aequorin-based luminescent assay for calcium mobilization was used to measure mobilization of intracellular Ca2+ (Bullock et al., Mol Pharmacol 65...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProkineticin receptor 2(Homo sapiens (Human))
The Regents of The University of California

US Patent
LigandPNGBDBM26335(3-[2-({5-[(4-ethylphenyl)methyl]-1-[(4-methoxyphen...)
Affinity DataKi:  1.61E+3nM ΔG°:  -8.22kcal/molepH: 7.4 T: 2°CAssay Description:Nonspecific binding was determined in the presence of 1 uM Bv8. Displacement curves were determined in triplicate. The inhibition constant (Ki) of th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProkineticin receptor 2(Homo sapiens (Human))
The Regents of The University of California

US Patent
LigandPNGBDBM26336(6-[(2-aminoethyl)amino]-3-[(4-ethylphenyl)methyl]-...)
Affinity DataKi:  2.34E+4nM ΔG°:  -6.57kcal/molepH: 7.4 T: 2°CAssay Description:Nonspecific binding was determined in the presence of 1 uM Bv8. Displacement curves were determined in triplicate. The inhibition constant (Ki) of th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProkineticin receptor 2(Homo sapiens (Human))
The Regents of The University of California

US Patent
LigandPNGBDBM26337(6-{[2-(4,5-dihydro-1H-imidazol-2-ylamino)ethyl]ami...)
Affinity DataKi:  7.12E+4nM ΔG°:  -5.88kcal/molepH: 7.4 T: 2°CAssay Description:Nonspecific binding was determined in the presence of 1 uM Bv8. Displacement curves were determined in triplicate. The inhibition constant (Ki) of th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed